Figure 4

Pathway analysis results that differentially expressed proteins at three time points including 6 h (panel A), 24 h (panel B) and 168 h (panel C) after 2/3 PH in rats can be sorted into different biological pathways. There are 18, 19, 14 root nodes in the sub-networks from 6-, 72- and 168-hour regenerating livers, respectively. The root nodes in above three subnetworks are all connected to YWHAE directly or indirectly. Red and green were identified as upregulated and downregulated proteins, respectively. Other gray denoted the proteins that were down-regulated only in SO sample or detected only in SO sample. Lines connecting the molecules indicate molecular relationships. Real lines indicate direct interactions and dashed lines indicate indirect interactions.