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Table 4 Effect of the hydroalcholic extracts of L. glutinosa on yeast-induced pyrexia in mice

From: In vivo analgesic, antipyretic, and anti-inflammatory potential in Swiss albino mice and in vitro thrombolytic activity of hydroalcoholic extract from Litsea glutinosa leaves

Treatment

Initial

Pyretic

1 h

2 h

3 h

Control (10 ml/kg)

33.33 ± 0.44

35.70 ± 0.46

35.66 ± 0.44

35.77 ± 0.56

35.39 ± 0.66

Standard (150 mg/kg)

33.28 ± 0.42

35.73 ± 0.55

34.80 ± 0.68

34.20 ± 0.63**

33.32 ± 0.67***

n-hexane extract (500 mg/kg)

33.80 ± 0.30

36.17 ± 0.40

35.90 ± 0.46

35.77 ± 0.25c

35.60 ± 0.17b

Ethyl acetate extract (500 mg/kg)

33.69 ± 0.79

35.57 ± 0.25

35.27 ± 0.15

35.00 ± 0.36*

34.87 ± 0.32c

Chloroform extract (500 mg/kg)

33.43 ± 1.37

35.37 ± 0.60

35.45 ± 0.70

35.23 ± 0.21c

35.17 ± 0.32b

Methanolic extract (500 mg/kg)

33.64 ± 0.80

36.93 ± 0.54

36.26 ± 0.68*c

34.13 ± 0.54**

32.78 ± 0.46***

  1. Values are expressed as mean ± SEM (Standard error mean); Values are calculated using one-way ANOVA followed by Dennett’s test; ***indicates P <0.001, **indicates P <0.01 and *indicates P <0.05 when compared to control; bindicates P <0.01and cindicates P <0.05 when compared to standard drug; n = 5.