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Table 4 Effect of the hydroalcholic extracts of L. glutinosa on yeast-induced pyrexia in mice

From: In vivo analgesic, antipyretic, and anti-inflammatory potential in Swiss albino mice and in vitro thrombolytic activity of hydroalcoholic extract from Litsea glutinosa leaves

Treatment Initial Pyretic 1 h 2 h 3 h
Control (10 ml/kg) 33.33 ± 0.44 35.70 ± 0.46 35.66 ± 0.44 35.77 ± 0.56 35.39 ± 0.66
Standard (150 mg/kg) 33.28 ± 0.42 35.73 ± 0.55 34.80 ± 0.68 34.20 ± 0.63** 33.32 ± 0.67***
n-hexane extract (500 mg/kg) 33.80 ± 0.30 36.17 ± 0.40 35.90 ± 0.46 35.77 ± 0.25c 35.60 ± 0.17b
Ethyl acetate extract (500 mg/kg) 33.69 ± 0.79 35.57 ± 0.25 35.27 ± 0.15 35.00 ± 0.36* 34.87 ± 0.32c
Chloroform extract (500 mg/kg) 33.43 ± 1.37 35.37 ± 0.60 35.45 ± 0.70 35.23 ± 0.21c 35.17 ± 0.32b
Methanolic extract (500 mg/kg) 33.64 ± 0.80 36.93 ± 0.54 36.26 ± 0.68*c 34.13 ± 0.54** 32.78 ± 0.46***
  1. Values are expressed as mean ± SEM (Standard error mean); Values are calculated using one-way ANOVA followed by Dennett’s test; ***indicates P <0.001, **indicates P <0.01 and *indicates P <0.05 when compared to control; bindicates P <0.01and cindicates P <0.05 when compared to standard drug; n = 5.
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