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Table 1 Effect of hydroalcholic extracts of L. glutinosa leaves on hot plate test

From: In vivo analgesic, antipyretic, and anti-inflammatory potential in Swiss albino mice and in vitro thrombolytic activity of hydroalcoholic extract from Litsea glutinosa leaves

Treatment

Response time (sec)

 

0 h

0.5 h

1 h

2 h

3 h

Control (10 ml/kg)

8.30 ± 0.63

7.42 ± 0.42

7.50 ± 0.39

7.50 ± 0.45

7.18 ± 0.33

Standard (10 mg/kg)

8.42 ± 0.29

11.59 ± 0.32**

13.58 ± 0.38**

14.98 ± 0.48***

16.38 ± 0.27***

n-hexane extract (250 mg/kg)

8.27 ± 0.32

10.25 ± 0.31**c

10.94 ± 0.13***a

11.27 ± 0.58**a

11.98 ± 0.37***b

n-hexane extract (500 mg/kg)

8.57 ± 0.63

11.01 ± 0.66**

11.43 ± 0.25***b

11.59 ± 0.76**b

12.22 ± 0.48***a

Ethyl acetate extract (250 mg/kg)

8.73 ± 0.30

10.05 ± 0.32**a

10.30 ± 0.74**a

11.13 ± 0.47**b

11.39 ± 0.65**b

Ethyl acetate extract (500 mg/kg)

8.70 ± 0.56

10.87 ± 0.46

11.36 ± 0.27***b

11.48 ± 0.59**b

11.89 ± 0.63**b

chloroform extract (250 mg/kg)

8.90 ± 0.40

10.58 ± 0.29***c

11.03 ± 0.40**b

11.33 ± 0.66*b

12.07 ± 0.28***a

chloroform extract (500 mg/kg)

8.87 ± 0.15

11.16 ± 0.47**

11.49 ± 0.24***b

11.69 ± 0.78**b

12.31 ± 0.54***b

Methanolic extract (250 mg/kg)

9.10 ± 0.33

11.48 ± 0.63**

13.20 ± 0.38**

14.24 ± 0.42***

15.06 ± 0.36***

Methanolic extract (500 mg/kg)

8.82 ± 0.18

11.54 ± 0.52**

13.38 ± 0.44**

14.56 ± 0.49***

15.54 ± 0.37***b

  1. Values are expressed as mean ± SEM (Standard error mean); Values are calculated using one-way ANOVA followed by Dennett’s test; ***indicates P <0.001 and **indicates P <0.01 when compared to control; aindicates P <0.001, bindicates P <0.01 and cindicates P <0.05 when compared to standard drug; p.o.; n = 6.