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Table 1 Effect of hydroalcholic extracts of L. glutinosa leaves on hot plate test

From: In vivo analgesic, antipyretic, and anti-inflammatory potential in Swiss albino mice and in vitro thrombolytic activity of hydroalcoholic extract from Litsea glutinosa leaves

Treatment Response time (sec)
  0 h 0.5 h 1 h 2 h 3 h
Control (10 ml/kg) 8.30 ± 0.63 7.42 ± 0.42 7.50 ± 0.39 7.50 ± 0.45 7.18 ± 0.33
Standard (10 mg/kg) 8.42 ± 0.29 11.59 ± 0.32** 13.58 ± 0.38** 14.98 ± 0.48*** 16.38 ± 0.27***
n-hexane extract (250 mg/kg) 8.27 ± 0.32 10.25 ± 0.31**c 10.94 ± 0.13***a 11.27 ± 0.58**a 11.98 ± 0.37***b
n-hexane extract (500 mg/kg) 8.57 ± 0.63 11.01 ± 0.66** 11.43 ± 0.25***b 11.59 ± 0.76**b 12.22 ± 0.48***a
Ethyl acetate extract (250 mg/kg) 8.73 ± 0.30 10.05 ± 0.32**a 10.30 ± 0.74**a 11.13 ± 0.47**b 11.39 ± 0.65**b
Ethyl acetate extract (500 mg/kg) 8.70 ± 0.56 10.87 ± 0.46 11.36 ± 0.27***b 11.48 ± 0.59**b 11.89 ± 0.63**b
chloroform extract (250 mg/kg) 8.90 ± 0.40 10.58 ± 0.29***c 11.03 ± 0.40**b 11.33 ± 0.66*b 12.07 ± 0.28***a
chloroform extract (500 mg/kg) 8.87 ± 0.15 11.16 ± 0.47** 11.49 ± 0.24***b 11.69 ± 0.78**b 12.31 ± 0.54***b
Methanolic extract (250 mg/kg) 9.10 ± 0.33 11.48 ± 0.63** 13.20 ± 0.38** 14.24 ± 0.42*** 15.06 ± 0.36***
Methanolic extract (500 mg/kg) 8.82 ± 0.18 11.54 ± 0.52** 13.38 ± 0.44** 14.56 ± 0.49*** 15.54 ± 0.37***b
  1. Values are expressed as mean ± SEM (Standard error mean); Values are calculated using one-way ANOVA followed by Dennett’s test; ***indicates P <0.001 and **indicates P <0.01 when compared to control; aindicates P <0.001, bindicates P <0.01 and cindicates P <0.05 when compared to standard drug; p.o.; n = 6.
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