Assessment of pharmacological activities of two medicinal plant of Bangladesh: Launaea sarmentosa and Aegialitis rotundifolia roxb in the management of pain, pyrexia and inflammation

Table 4 Effects of AELS, AEAR and Standard drug on carrageenan induced inflammation on rats

Group	Treatment	Dose [mg/kg]	Paw volume at different time interval (in ml) (Mean ± S.E.M)				Inhibition (%)
			0 hour	1 hour	2 hour	3 hour	1 hour	2 hour	3 hour
I	Control	---	.77 ± .048	1.07 ± .059	1.27 ± .052	1.57 ± .011	---	---	---
II	Standard	10	.61 ± .003	.73 ± .02**	.86 ± .03***	0.94 ± .02***	31.8	32.3	40.13
III	AELS	100	.72 ± .04	.95 ± .05*	1.11 ± .05*	1.21 ± .04*	11.21	12.59	22.93
IV	AELS	200	.67 ± .03	.91 ± .03**	1.06 ± .06**	1.14 ± .005**	15	16.5	27.39
V	AELS	400	.73 ± .03	.87 ± .04**	.98 ± .04***	1.06 ± .05***	18.7	22.8	32.48
VI	AEAR	100	0.74 ± 0.02	0.98 ± .02	1.14 ± .03	1.31 ± .05	8.41	10.23	16.56
VII	AEAR	200	.69 ± .03	.93 ± .05*	1.1 ± .06*	1.21 ± .04*	13.0	13.39	22.93
VIII	AEAR	400	.64 ± .03	.91 ± .03**	1.06 ± .06**	1.15 ± .06**	15.0	16.5	26.75

Values are expressed as mean ± S.E.M (n = 6). *P < 0.05 (significant), **P < 0.01 (more significant) and ***P < 0.001 (most significant), compared with vehicle control (ANOVA followed by Dunnet’s t-test).

ISSN: 0717-6287