Assessment of pharmacological activities of two medicinal plant of Bangladesh: Launaea sarmentosa and Aegialitis rotundifolia roxb in the management of pain, pyrexia and inflammation

Table 3 Effects of AELS, AEAR and aspirin on acetic acid induced writhing method

Group	Treatment	Dose [mg/kg]	No. of writhes [15 min] (Mean ± S.E.M)	Inhibition (%)
I	Control	---	48.33 ± 1.13	---
II	Standard	50	14.87 ± 0.09***	69.23%
III	AELS	100	25.1 ± 0.12*	48.05%
IV	AELS	200	21.57 ± 0.11**	55.36%
V	AELS	400	17.83 ± 0.1***	63.10%
VI	AEAR	100	28.63 ± 0.14	40.76%
VII	AEAR	200	25.20 ± 0.13*	47.86%
VIII	AEAR	400	20.73 ± 0.10**	57.10%

Values are expressed as mean ± S.E.M (n = 6). *P < 0.05 (significant), **P < 0.01 (more significant) and ***P < 0.001 (most significant) compared with vehicle control (ANOVA followed by Dunnet’s t-test).

ISSN: 0717-6287