In vivo antipyretic, antiemetic, in vitro membrane stabilization, antimicrobial, and cytotoxic activities of different extracts from Spilanthes paniculata leaves

Table 2 Antiemetic activities of ethanolic extract and fractions of S. paniculata leaves

Treatments	Doses	Mean number of retches ± SEM	% inhibition of emesis
Control	10 ml/kg	71.4 ± 1.76	-
Standard	50 mg/kg	23.4 ± 2.85	67.23
Crude extract	200 mg/kg	46.2 ± 1.80	39.78
Crude extract	400 mg/kg	44.6 ± 2.10	37.54
n-hexane extract	200 mg/kg	46.8 ± 2.02	34.45**
n-hexane extract	400 mg/kg	44.6 ± 2.03	37.53**
Ethyl acetate extract	200 mg/kg	54.4 ± 1.86	23.80**
Ethyl acetate extract	400 mg/kg	53.6 ± 2.07	24.93**

Here, **Significant difference at P < 0.001 vs. control; SEM = standard error mean.