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Table 2 Antiemetic activities of ethanolic extract and fractions of S. paniculata leaves

From: In vivo antipyretic, antiemetic, in vitro membrane stabilization, antimicrobial, and cytotoxic activities of different extracts from Spilanthes paniculata leaves

Treatments Doses Mean number of retches ± SEM % inhibition of emesis
Control 10 ml/kg 71.4 ± 1.76 -
Standard 50 mg/kg 23.4 ± 2.85 67.23
Crude extract 200 mg/kg 46.2 ± 1.80 39.78
400 mg/kg 44.6 ± 2.10 37.54
n-hexane extract 200 mg/kg 46.8 ± 2.02 34.45**
400 mg/kg 44.6 ± 2.03 37.53**
Ethyl acetate extract 200 mg/kg 54.4 ± 1.86 23.80**
400 mg/kg 53.6 ± 2.07 24.93**
  1. Here, **Significant difference at P < 0.001 vs. control; SEM = standard error mean.