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Table 1 Effect of the crude, n-hexane, and ethyl acetate extracts of S. paniculata on yeast-induced pyrexia in mice

From: In vivo antipyretic, antiemetic, in vitro membrane stabilization, antimicrobial, and cytotoxic activities of different extracts from Spilanthes paniculata leaves

Treatment Dose mg/kg Mean ± SEM rectal temperature (°C)
   0 h 1 h 2 h 3 h 4 h 5 h
Control - 37.4 ± 0.5 36.9 ± 0.5 37.03 ± 0.12 37.07 ± 0.12 37.03 ± 0.13 36.9 ± 0.7
Standard (Paracetamol) 150 37.2 ± 0.1 36.5 ± 0.6** 36.8 ± 0.26 36.77 ± 0.18** 36.9 ± 0.31 36.7 ± 0.70**
Crude extract 400 37.03 ± 0.2 36.8 ± 0.6 37.2 ± 0.07 36.93 ± 0.15 37 ± 0.26 36.8 ± 0.61
n-hexane extract 400 36.9 ± 0.4 36.7 ± 0.6** 36.7 ± 0.37 36.77 ± 0.12** 36.82 ± 0.41 36.7 ± 0.63**
Ethyl acetate extract 400 37 ± 0.3 36.8 ± 0.6 36.8 ± 0.26 37.03 ± 0.24 37.1 ± 0.23 36.8 ± 0.63
  1. Here, **Significant difference at P < 0.05 vs. control (n = 5); SEM = standard error mean.
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