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Figure 4 | Biological Research

Figure 4

From: Normalization of the levels of inflammatory molecules in Mycobacterium smegmatis-infected U937 cells by fibrate pretreatment

Figure 4

Tumor necrosis factor-α (TNF-α) and myeloid differentiation primary response gene 88 (MyD88) protein expression levels were regulated by pretreatment with fibrates (1 μM concentration, 24 h) in M smegmatis -infected U937 cells. Results at 1 h after infection (A) and 6 h after infection (B). β-actin was used as the loading control. Each protein density of fibrate-treated or untreated (vehicle) M smegmatis-infected cells were normalized to that of uninfected vehicle cells. Each result represents the mean ± SD of three experiments. Significance was calculated as *p value < 0.05 compared to vehicle control (fibrate-untreated uninfected U937 cells), using Student’s unpaired t-test. Significance was calculated as #p value < 0.05 compared to vehicle control (fibrate-untreated infected U937 cells) using Student’s unpaired t-test. Beza, bezafibrate; Feno, fenofibrate; Gem, gemfibrozil.

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