Fibrate pretreatment affects acetyl coenzyme A acetyl transferase-1 (ACAT-1), peroxisome proliferator-activated receptor-α (PPAR-α), tumor necrosis factor-α (TNF-α), and myeloid differentiation primary response gene 88 (MyD88) expression patterns in U937 cells. (A) The expression patterns of various factors at 12 h or 24 h are shown after treatment with fibrates. The expression patterns associated with all factors decreased after 12 h and 24 h compared with those in the untreated control. β-actin was used as the loading control. (B) Each protein density of fibrate-treated cells were normalized to that of untreated vehicle cells. Each result represents the mean ± SD of three experiments. Significance was calculated as *p value < 0.05 compared to the control by Student’s unpaired t-test. Beza, bezafibrate; Feno, fenofibrate; Gem, gemfibrozil.