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Figure 2 | Biological Research

Figure 2

From: Ethyl acetate fraction from Angelica sinensis inhibits IL-1β-induced rheumatoid synovial fibroblast proliferation and COX-2, PGE2, and MMPs production

Figure 2

EAAS inhibited IL-1β-induced production of MMPs and COX-2 in RASFs. IL-1β enhanced the expression of MMP-1, MMP −3, TIMP-1, and COX-2 protein compared with the results without IL-1β. EAAS inhibited the IL-1β-induced expression of MMP-1, MMP-3, and COX-2 protein. Results are presented as mean ± SD. n = 3. *p < 0.05 versus no IL-1β and EAAS, †p < 0.05 versus no IL-1β and EAAS, ‡p < 0.05 versus IL-1β without EAAS.

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