Table 7 TDT analysis in family trios for SNP association with asthma
SNP allele | Valid trios (n) | TDT-test value | TDT p-value | OR (95% CI) |
|---|---|---|---|---|
Overall asthma | ||||
ADAM33-V4*C | 41 | 3.429 | 0.044 | 1.800 (0.956-3.384) |
Persistent asthma | ||||
ADAM33-V4*C | 30 | 5.452 | 0.015 | 2.444 (1.126-5.309) |
Mild asthma | ||||
ADAM33-V4*C | 19 | 7.200 | 0.006 | 4.000 (1.337-11.965) |
Moderate-severe asthma | ||||
IL4-590*T | 19 | 3.857 | 0.039 | 2.500 (0.970-6.443) |
IL4-RP2*183 | 17 | 5.556 | 0.015 | 3.500 (1.152-10.633) |