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Table 7 TDT analysis in family trios for SNP association with asthma

From: Genetic polymorphisms and asthma: findings from a case–control study in the Madeira island population

SNP allele Valid trios (n) TDT-test value TDT p-value OR (95% CI)
Overall asthma     
ADAM33-V4*C 41 3.429 0.044 1.800 (0.956-3.384)
Persistent asthma     
ADAM33-V4*C 30 5.452 0.015 2.444 (1.126-5.309)
Mild asthma     
ADAM33-V4*C 19 7.200 0.006 4.000 (1.337-11.965)
Moderate-severe asthma     
IL4-590*T 19 3.857 0.039 2.500 (0.970-6.443)
IL4-RP2*183 17 5.556 0.015 3.500 (1.152-10.633)
  1. Only significant associations are reported, in bold.