Table 4 Mean FEV 1 and FVC indexes across SNP genotypes
SNP genotypes | Lung function indexes | ||
|---|---|---|---|
FEV1(mean +/-s.d.) | FVC (mean+/-s.d.) | ||
n | 98 | 98 | |
IL13-c.144 G/A | GG | 98.42 + -13.95 | 96.33 + -11.88 |
GA | 93.44 + -16.58 | 92.15 + -14.79 | |
AA | 92.50 + -7.78 | 89.50 + -12.02 | |
IL4-590 C/T | CC | 99.92 + -14.28 | 96.87 + -11.28 |
CT | 91.69 + -14.41 | 92.13 + -14.79 | |
TT | 90.00 + -12.00 | 87.67 + 16.04 | |
F p-value | 0.024 | ||
Dominant model CT/TT vs CC | 0.006 | ||
IL4-RP2 253/183 | 253253 | 99.75 + -14.15 | 97.07 + -11.34 |
183253 | 90.59 + -14.52 | 90.74 + -14.89 | |
183183 | 90.00 + -12.00 | 87.67 + -16.04 | |
F p-value | 0.015 | ||
Dominant model 183253/183183 vs 253253 | 0.004 | ||
ADRB2-c.16 A/G | AA | 95.16 + -19.79 | 91.74 + -16.20 |
AG | 95.91 + -12.83 | 94.91 + -11.95 | |
GG | 99.47 + -13.94 | 97.19 + -11.62 | |
ADAM33-V4 C/G | GG | 99.00 + -0 c | 98.00 + -0c |
CG | 94.65 + -15.66 | 94.26 + -10.19 | |
CC | 97.61 + -14.53 | 95.24 + -13.61 | |
ADAM33-S1c.710 G/A | GG | 97.13 + -14.81 | 95.22 + -13.05 |
GA | 94.29 + -13.96 | 92.71 + -8.92 | |
AA | - | - | |
GSDML-236 C/T | CC | 99.13 + -13.20 | 94.25 + -12.07 |
CT | 96.30 + -17.48 | 94.13 + -14.34 | |
TT | 96.75 + -11.34 | 96.56 + -11.04 | |
STAT6-21 C/T | CC | 97.34 + -15.74 | 95.00 + -14.28 |
CT | 96.49 + -13.52 | 94.24 + -11.73 | |
TT | 96.92 + -15.73 | 97.69 + -11.01 | |