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Table 2 Clinical characterization of the asthmatics study population

From: Genetic polymorphisms and asthma: findings from a case–control study in the Madeira island population

 

Study sample set

 

Overall asthma

Intermittent asthma

Persistent asthma

Mild

Moderate-severe

p-value

Sample size (n,%)

98 (100.0)

24 (24.5)

74 (75.5)

44 (59.9)

30 (40.5)

 

Male/Female (%)

59.2/40.8

62.5/37.5

58.1/41.9

54.5/45.5

63.3/36.7

 

Mean age (years + -s.d.)

13.6 + -4.3

14.1 + -3.5

13.4 + - 4.5

14.3 + -4.6

12.0 + - 4.1

 

Mean FEV1 (%)

96.9 + -14.7

98.5 + -16.3

96.4 + -14.2

99.9 + -10.7

91.2 + - 17.1

0.008

Mean FVC (%)

95.0 + -12.8

97.4 + -12.1

94.3 + -13.0

97.3 + -9.9

89.8 + -15.6

0.025

  1. Asthma classification according to GINA [75].
  2. A Shapiro-Wilk test showed that FEV1 is normally distributed (p > 0.05) while FVC is not (p = 0.008). Thus, a t-test was used for the analysis of FEV1 while a Mann–Whitney test was used for FVC. Statistically significant p-values were found for comparisons between mild persistent and moderate-severe persistent asthma, denoted in bold.