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Table 7 Anti-inflammatory activity of SAET

From: Antioxidant, antimicrobial, toxicity and analgesic properties of ethanol extract of Solena amplexicaulis root

Groups

Dose of extract (mg/kg) p.o.

Change in paw thickness (mm) ± SD (% inhibition)

1 hour

2 hour

3 hour

4 hour

Carrageenan control

 

1.34 ± 0.1

2.3 ± 0.118

3.64 ± 0.147

3.23 ± 0.161

(.01 ml of 1% w/v)

Carrageenan

200

1.14 ± 0.103 (14.93%)

1.74 ± 0.217 (26.44%)a

2.50 ± 0.106 (31.3%)a

1.97 ± 0.115 (39.0%)a

(0.1 ml of 1% w/v) + aqueous extract

Carrageenan

400

1.00 ± 0.12 (25.6%)

1.54 ± 0.163 (35.02%)a

1.81 ± 0.009 (50.09%)a

1.41 ± 0.188 (56.34%)a

(0.1 ml of 1% w/v) + aqueous extract

Carrageenan

10

0.59 ± 0.118 (55.97%)a

0.8 ± 0.121 (66.24%)a

1.14 ± 0.121 (68.82%)a

0.9 ± 0.118 (72.13%)a

(0.1 ml of 1% w/v) + diclofenac sodium

  1. All values are expressed as mean ± SD; P < 0.05.
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Biological Research

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