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Table 2 Effect of total extract and primary fractions obtained from Cryptostegia grandiflora leaves on MPO activity in ear tissue

From: In vivo and in vitro anti-inflammatory activity of Cryptostegia grandiflora Roxb. ex R. Br. leaves

Treatment

Dose (mg/ear)

MPO activity (U/mg of tissue)

Inhibition percentage (%)

Control (TPA + acetone)

— — —

18150 ± 2012.3

Indomethacin

0.5

4040 ± 406.9

77.7 ± 2.2***

Cryptostegia grandiflora

Total extract

1.0

11040 ± 987.8

39.1 ± 5.4***

Ether fraction

1.0

600 ± 89.4

96.6 ± 0.4***

Dichloromethane fraction

1.0

666 ± 98.8

96.3 ± 0.5***

  1. Results are expressed as mean ± S.M.E. (n = 6) (***p < 0.001 ANOVA, statistically significant compared with control group).