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Table 2 Effect of total extract and primary fractions obtained from Cryptostegia grandiflora leaves on MPO activity in ear tissue

From: In vivo and in vitro anti-inflammatory activity of Cryptostegia grandiflora Roxb. ex R. Br. leaves

Treatment Dose (mg/ear) MPO activity (U/mg of tissue) Inhibition percentage (%)
Control (TPA + acetone) — — — 18150 ± 2012.3
Indomethacin 0.5 4040 ± 406.9 77.7 ± 2.2***
Cryptostegia grandiflora
Total extract 1.0 11040 ± 987.8 39.1 ± 5.4***
Ether fraction 1.0 600 ± 89.4 96.6 ± 0.4***
Dichloromethane fraction 1.0 666 ± 98.8 96.3 ± 0.5***
  1. Results are expressed as mean ± S.M.E. (n = 6) (***p < 0.001 ANOVA, statistically significant compared with control group).