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Table 1 Homozygote Pro/Pro72 versus Heterozygote Arg/Pro72

From: Assessment of changes in the brca2 and p53 genes in breast invasive ductal carcinoma in northeast Brazil

Parameter

Codon 72 polymorphism

p

RR (IC95%)

OR (IC95%)

x2

Pro/Pro72

Arg/Pro72

(n = 15)

(n = 30)

Age (in years)

 

 30–50

6

13

0.903

0.9474 (0.3965 to 2.263)

0.9231 (0.2548 to 3.344)

0.0148

  >51

8

16

Tumor size (cm)

  <5

11

26

0.2701

0.5946 (0.2536 to 1.394)

0.4231 (0.08932 to 2.004)

1.216

  >5

4

4

Lymph node involvement

 Negative

7

10

0.3845

1.441 (0.6372 to 3.260)

1.750 (0.4928 to 6.215)

0.7563

 Positive

8

20

Metastasis

 Negative

11

14

0.046

2.787 (0.9011 to 8.617)

4.190 (0.9686 to 18.13)

3.960

 Positive

3

16

  1. Arg (Arginine); Pro (Proline).