Table 2 Cytotoxic activity of extracts from C. sappan
From: Methanol extract from Vietnamese Caesalpinia sappan induces apoptosis in HeLa cells
Extracts | IC50value (μg/mL)a | |||||||
|---|---|---|---|---|---|---|---|---|
HL-60 | HeLa | MCF7 | LLC | HepG2 | KPL4 | HT-29 | KB | |
MeOH ex. | 40.7 ± 5.8 | 26.5 ± 3.2 | 37.7 ± 3.1 | > 100 | 65.1 ± 3.5 | > 100 | > 100 | 76.7 ± 4.8 |
EtOH ex. | 68.5 ± 5.1 | 39.2 ± 2.0 | > 100 | 25.1 ± 3.8 | > 30 | > 100 | > 100 | > 100 |
Water ex. | > 100 | 37.8 ± 3.6 | > 100 | > 100 | 78.6 ± 4.3 | > 100 | > 100 | > 100 |
Camptothecinb | 6.2 ± 0.2 | 3.4 ± 0.2 | 4.5 ± 0.3 | 5.1 ± 0.7 | 6.2 ± 0.4 | 14.5 ± 1.7 | 10.7 ± 0.8 | 4.5 ± 0.4 |